London: Commonly used painkillers such as ibuprofen and diclofenac may increase the risk of dying from a heart attack or stroke by fourfold, a new study has claimed.
In one of the most comprehensive studies on the cardiovascular effects of painkillers, scientists from Bern University in Switzerland analysed data from 31 trials involving more than 116,000 patients taking such drugs and found that heart patients using a high-dose painkiller daily for a year could triple their risk of a stroke.
Although the overall numbers of people suffering heart attacks or strokes while on the drugs is small, the team found that there are important risks associated with taking them, the Telegraph reported.The drugs examined were naproxen, ibuprofen, diclofenac, celecoxib, etoricoxib and two others called rofecoxib or Vioxx, and lumiracoxib.
The drugs, called non-steroidal anti-inflammatory drugs(NSAIDS) and a subgroup of newer onescalledCOX-2inhibitors, areknown to affect the heart and one of them, Vioxx, was removed from sale in 2004 because of the increased risk of heart attacks. PTI
Heart patients using a high-dose painkiller a day for a year could triple the risk of a stroke
Thursday, January 13, 2011
Monday, January 3, 2011
Can Too much calium cause heart disease
Don’t throw out those calcium supplements just yet.
Oh, the ruckus a single study can raise. A report about calcium and cardiovascular disease had people from San Diego to Caribou, Maine worriedly calling their doctors or throwing away the calcium supplements they were taking to keep their bones strong.
Here’s what prompted the concern: New Zealand researchers pooled the results of 11 randomized, controlled trials—the so-called gold standard of medical research—comparing the effects of calcium supplements and placebo on preventing osteoporosis or colon cancer. All the trials also had information on the volunteers’ cardiovascular health. As reported online in the BMJ, more of the volunteers taking calcium had heart attacks, stroke, or died suddenly than did those taking the placebo. Media reports duly noted a 30% increased risk of cardiovascular disease with calcium supplements, which sounds scary. Another way to put the findings: 5.8% of those taking calcium had a cardiovascular event, compared with 5.5% of those taking placebo.
This publication is just another piece of the calcium puzzle. It isn’t a practice changer. Some prior studies have shown that taking calcium supplements is linked to cardiovascular disease, others haven’t.
The connection between calcium and cardiovascular disease is plausible. Calcium deposits are part of artery-clogging plaque. They also contribute to stiffening of the arteries and interfere with the action of heart valves. But whether there is a direct connection between the amount of calcium in the bloodstream (calcium supplements increase blood calcium levels) and cardiovascular problems isn’t yet known.
An even bigger unanswered question is how much calcium the average person needs each day to keep bones strong and healthy. At one end of the spectrum, the World Health Organization says 400 to 500 milligrams (mg) of calcium a day are needed to prevent osteoporosis. At the other end, the official recommendation for Americans is 1,000 mg/day from ages 19 to 50 and 1,200 mg/day after that.
Given the uncertainty about the balance of benefits and risks of calcium supplements, it’s probably best not to rely just on this mineral to keep your bones strong and prevent bone-thinning osteoporosis. Other options include:
•Weight-bearing exercise, like walking, running, tennis, and others, is one of the best things you can do for your bones.
•Getting enough vitamin D, from sun and supplements, is also good for bones and overall health. (As with everything, don’t overdo it—no more than 10 to 15 minutes of sunshine without sunscreen, and/or 800 to 1,000 IU of a vitamin D supplement.)
•Vitamin K from green leafy vegetables such as spinach, Swiss chard, and kale is also important for bone health.
A single study rarely changes health recommendations. This New Zealand study alone definitely shouldn’t change advice on calcium supplement. It should, though, nudge you to talk with your doctor about calcium, and do other things to protect your bones.
Oh, the ruckus a single study can raise. A report about calcium and cardiovascular disease had people from San Diego to Caribou, Maine worriedly calling their doctors or throwing away the calcium supplements they were taking to keep their bones strong.
Here’s what prompted the concern: New Zealand researchers pooled the results of 11 randomized, controlled trials—the so-called gold standard of medical research—comparing the effects of calcium supplements and placebo on preventing osteoporosis or colon cancer. All the trials also had information on the volunteers’ cardiovascular health. As reported online in the BMJ, more of the volunteers taking calcium had heart attacks, stroke, or died suddenly than did those taking the placebo. Media reports duly noted a 30% increased risk of cardiovascular disease with calcium supplements, which sounds scary. Another way to put the findings: 5.8% of those taking calcium had a cardiovascular event, compared with 5.5% of those taking placebo.
This publication is just another piece of the calcium puzzle. It isn’t a practice changer. Some prior studies have shown that taking calcium supplements is linked to cardiovascular disease, others haven’t.
The connection between calcium and cardiovascular disease is plausible. Calcium deposits are part of artery-clogging plaque. They also contribute to stiffening of the arteries and interfere with the action of heart valves. But whether there is a direct connection between the amount of calcium in the bloodstream (calcium supplements increase blood calcium levels) and cardiovascular problems isn’t yet known.
An even bigger unanswered question is how much calcium the average person needs each day to keep bones strong and healthy. At one end of the spectrum, the World Health Organization says 400 to 500 milligrams (mg) of calcium a day are needed to prevent osteoporosis. At the other end, the official recommendation for Americans is 1,000 mg/day from ages 19 to 50 and 1,200 mg/day after that.
Given the uncertainty about the balance of benefits and risks of calcium supplements, it’s probably best not to rely just on this mineral to keep your bones strong and prevent bone-thinning osteoporosis. Other options include:
•Weight-bearing exercise, like walking, running, tennis, and others, is one of the best things you can do for your bones.
•Getting enough vitamin D, from sun and supplements, is also good for bones and overall health. (As with everything, don’t overdo it—no more than 10 to 15 minutes of sunshine without sunscreen, and/or 800 to 1,000 IU of a vitamin D supplement.)
•Vitamin K from green leafy vegetables such as spinach, Swiss chard, and kale is also important for bone health.
A single study rarely changes health recommendations. This New Zealand study alone definitely shouldn’t change advice on calcium supplement. It should, though, nudge you to talk with your doctor about calcium, and do other things to protect your bones.
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